Effects of a mutation in the Drosophila porin gene encoding mitochondrial voltage-dependent anion channel protein on phototransduction.

@article{Lee2007EffectsOA,
  title={Effects of a mutation in the Drosophila porin gene encoding mitochondrial voltage-dependent anion channel protein on phototransduction.},
  author={Sunji Lee and Hung-Tat Leung and Eunju Kim and Jeyoun Jang and Eunsung Lee and Kwanghee Baek and William L. Pak and Jaeseung Yoon},
  journal={Developmental neurobiology},
  year={2007},
  volume={67 11},
  pages={1533-45}
}
Mitochondrial porins, also know as VDACs (voltage-dependent anion channels), play an important role in regulating energy metabolism, apoptosis, and the transport of metabolites across the mitochondrial outer membrane. So far three distinct isoforms of VDAC (VDAC1-3) have been reported in vertebrates, but their functions remain unknown. The annotation database of the Drosophila melanogaster genome sequence has identified four genes (porin, CG17137, CG17139, and CG17140) encoding different… CONTINUE READING