Effects of a high fat-sucrose diet on cortical bone morphology and biomechanics

  title={Effects of a high fat-sucrose diet on cortical bone morphology and biomechanics},
  author={K Li and Ronald F. Zernicke and R. James Barnard and Anna F-Y. Li},
  journal={Calcified Tissue International},
High fat-sucrose (HFS) diets can reportedly produce glucose intolerance and hyperinsulinemia that may indirectly have deleterious effects on bone. The effects of a high-fat diet on calcium absorption, bone calcium content, and bone mechanical properties, however, remain controversial. Thus, we examined the morphological and biomechanical adaptations in limb bones of rats that were fed a HFS diet. Female Sprague-Dawley rats (8 weeks old) were randomly assigned to two groups, either a control… CONTINUE READING


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