Effects of a gluten-free diet on gut microbiota and immune function in healthy adult human subjects

@article{DePalma2009EffectsOA,
  title={Effects of a gluten-free diet on gut microbiota and immune function in healthy adult human subjects},
  author={Giada De Palma and Inmaculada Nadal and Mar{\'i}a Carmen Collado and Yolanda Sanz},
  journal={British Journal of Nutrition},
  year={2009},
  volume={102},
  pages={1154 - 1160}
}
Diet influences the composition of the gut microbiota and host's health, particularly in patients suffering from food-related diseases. Coeliac disease (CD) is a permanent intolerance to cereal gluten proteins and the only therapy for the patients is to adhere to a life-long gluten-free diet (GFD). In the present preliminary study, the effects of a GFD on the composition and immune function of the gut microbiota were analysed in ten healthy subjects (mean age 30·3 years) over 1 month. Faecal… 

Effects of a gluten-free diet on gut microbiota and immune function in healthy adult humans

Fecal samples of subjects under a GFD, which represent an altered microbiota, also exerted lower immune stimulatory effects on peripheral blood mononuclear cells than those of subjects on a regular gluten-containing diet.

The Effect of Gluten-Free Diet on Health and the Gut Microbiota Cannot Be Extrapolated from One Population to Others

The biomedical community is persuaded to think that the results from the effect of GFD on health and the gut microbiota cannot be extrapolated from one population to others, and encourages the conception of more collaborative efforts to study local populations in an effort to reach biologically and medically useful conclusions that truly contribute to improve health in patients afflicted with GRD.

Probiotics, Prebiotics and Other Dietary Supplements for Gut Microbiota Modulation in Celiac Disease Patients

Evidence regarding the use of prebiotics and probiotics in patients with CD is still insufficient to justify their use in clinical practice, but the inclusion of preBiotics in GFD could also be easy to administer and cost-effective as an adjunctive treatment for CD.

The influence of a short-term gluten-free diet on the human gut microbiome

A GFD changes the gut microbiome composition and alters the activity of microbial pathways and observes strong relations between the predicted activity of pathways and biomarker measurements.

Effects of gluten-free, dairy-free diet on childhood nephrotic syndrome and gut microbiota

Investigations are needed to fill the gaps in knowledge concerning the associations between the gut microbiome, environmental exposures, epigenetics, racial influences, and the propensity for immune dysregulation with its inherent risk to the developing individual.

Faecal Concentrations of Short-chain Fatty Acids and Selected Bacteria in Healthy and Celiac Children

Changes in microbiota and SCFAs are clearly related to the pathogenesis of CD, as being potential pro-inflammatory agents in CD, acetic and propionic acid may serve as important disease-related markers.

Dietary Gluten-Induced Gut Dysbiosis Is Accompanied by Selective Upregulation of microRNAs with Intestinal Tight Junction and Bacteria-Binding Motifs in Rhesus Macaque Model of Celiac Disease

It is predicted that with the introduction of effective treatments in future studies the diversity of gut microbiomes in GS macaques will approach those of healthy individuals.

Salivary and fecal microbiota and metabolome of celiac children under gluten-free diet.

The Modification of the Gut Microbiota via Selected Specific Diets in Patients with Crohn’s Disease

The impact of diet interventions on the microbiota and, potentially, on the future course of the disease should be considered when nutritional guidelines for IBD patients are designed.
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