Effects of a fixed combination of peppermint oil and caraway oil on symptoms and quality of life in patients suffering from functional dyspepsia.

  title={Effects of a fixed combination of peppermint oil and caraway oil on symptoms and quality of life in patients suffering from functional dyspepsia.},
  author={Gerald J. Holtmann and Sebastian Haag and Birgit Adam and Petra Funk and Veronika Wieland and Claus-Juergen Heydenreich},
  journal={Phytomedicine : international journal of phytotherapy and phytopharmacology},
  volume={10 Suppl 4},
Changes in beneficial bioactive compounds in eight traditional herbal liqueurs during a one-month maceration process.
The compositions of eight herbal liqueurs were highly related to the presence of different herbal ingredients and their solubility in the extract over time and the two liquesurs (common centaury and caraway) had the highest phenolic contents after 3 weeks of maceration.
Traditional uses of Iraqi medicinal plants
This study illustrates the importance of Iraqi medicinal plants in the treatment and management of human diseases and ailments as known by traditional medicine.
Effectiveness of Menthacarin on symptoms of irritable bowel syndrome
The reduction of IBS-associated symptoms in FD patients suggests Menthacarin as a treatment option for IBS patients, and the subgroup analysis indicates beneficial treatment effects of MenthACarin that are similar to those found for FD patients in the primary analyses.
A randomized placebo‐controlled trial on the effects of Menthacarin, a proprietary peppermint‐ and caraway‐oil‐preparation, on symptoms and quality of life in patients with functional dyspepsia
  • G. Rich, A. Shah, G. Holtmann
  • Medicine, Psychology
    Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society
  • 2017
This work assess and compare the efficacy of a fixed peppermint/caraway‐oil‐combination (Menthacarin) on symptoms and quality of life (QoL) in patients with FD symptoms consistent with epigastric pain syndrome (EPS) and postprandial distress syndrome (PDS).
Broad-Spectrum Inhibition of the CC-Chemokine Class Improves Wound Healing and Wound Angiogenesis
Findings show that broad-spectrum CC-chemokine inhibition may be beneficial for the promotion of wound healing.
Dietary amelioration of Helicobacter infection.
Herbal medicines for the treatment of functional and inflammatory bowel disorders.
  • G. Holtmann, N. Talley
  • Medicine
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • 2015
A new insight is opened for the therapeutic efficacy of Carum carvi through a new insight into the chemical constituents of the plant and its constituents.
Peppermint Oil : Clinical Uses in the Treatment of Gastrointestinal Diseases
Although more research may be beneficial, peppermint oil shows evidence justifying a more expanded using gastrointestinal disease management, as well as anti-inflammatory and anti-bacterial effects.


Treatment of functional dyspepsia with a fixed peppermint oil and caraway oil combination preparation as compared to cisapride. A multicenter, reference-controlled double-blind equivalence study.
The combination preparation consisting of peppermint oil and caraway, oil appears to be comparable with cisapride and provides an effective means for treatment of functional dyspepsia.
Effects of intraduodenal application of peppermint oil (WS® 1340) and caraway oil (WS® 1520) on gastroduodenal motility in healthy volunteers
It could be shown that both WS® 1340 and WS® 1520 contribute to the efficacy of Enteroplant®, which act locally in the stomach and duodenum to produce smooth‐muscle relaxation.
Effects of peppermint oil and caraway oil on gastroduodenal motility
Enteric‐ coated and non‐enteric‐coated peppermint–caraway oil combinations are safe preparations, acting locally to cause smooth muscle relaxation.
Peppermint oil and caraway oil in functional dyspepsia — efficacy unaffected by H. pylori
In both sub-groups, which revealed comparable baseline characteristics, patients given PCC showed notably larger improvements in all three outcome measures, and the analyses followed the intention-to-treat principle.
Effect of peppermint oil and caraway oil on gastrointestinal motility in healthy volunteers: a pharmacodynamic study using simultaneous determination of gastric and gall‐bladder emptying and orocaecal transit time
Background : Although peppermint oil and caraway oil are frequently used in herbal drugs for abdominal discomfort and pain, the pharmacological insights into their effects on the gastrointestinal
Efficacy of a fixed peppermint oil/caraway oil combination in non-ulcer dyspepsia.
The efficacy and safety of the standardized herbal combination preparation of Enteroplant, consisting of peppermint oil (90 mg) and caraway (50 mg) in an enteric coated capsule, have been studied in