Effects of a continuous infusion of dopamine on the ventilatory and carotid body responses to hypoxia in cats.

@article{Ide1995EffectsOA,
  title={Effects of a continuous infusion of dopamine on the ventilatory and carotid body responses to hypoxia in cats.},
  author={Tatsuya Ide and Machiko Shirahata and C L Chou and Robert S. Fitzgerald},
  journal={Clinical and experimental pharmacology & physiology},
  year={1995},
  volume={22 9},
  pages={658-64}
}
1. We investigated how a continuous infusion of dopamine (DA; 5 micrograms/kg per min), which is often used clinically, would affect the ventilation and carotid chemoreceptor neural activity in anaesthetized cats. 2. In anaesthetized, spontaneously breathing cats, tidal volume (VT) and respiratory frequency (f) were continuously monitored at five levels of inspired oxygen (PIO2 = 110, 130, 150, 170, 760 mmHg) during Da or saline infusion. VT and f were sampled for 1 min after 3 min exposure to… CONTINUE READING
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