Effects of a Mangifera indica L. stem bark extract and mangiferin on radiation-induced DNA damage in human lymphocytes and lymphoblastoid cells.

@article{Rodeiro2014EffectsOA,
  title={Effects of a Mangifera indica L. stem bark extract and mangiferin on radiation-induced DNA damage in human lymphocytes and lymphoblastoid cells.},
  author={Idania Rodeiro and Rene Luis Delgado and Gabino Garrido Garrido},
  journal={Cell proliferation},
  year={2014},
  volume={47 1},
  pages={48-55}
}
OBJECTIVES Mangifera indica L. (mango) stem bark aqueous extract (MSBE) that has antioxidant, anti-inflammatory and immunomodulatory properties, can be obtained in Cuba. It is rich in polyphenols, where mangiferin is the main component. In this study, we have tested DNA damage and protection effects of MSBE and mangiferin on primary human lymphocytes and lymphoblastoid cells. MATERIAL AND METHODS Cell suspensions were incubated with the products (50-1000 μg/ml) for experiments on damage… CONTINUE READING
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