Effects of a Mangifera indica L. stem bark extract and mangiferin on radiation‐induced DNA damage in human lymphocytes and lymphoblastoid cells
@article{Rodeiro2014EffectsOA, title={Effects of a Mangifera indica L. stem bark extract and mangiferin on radiation‐induced DNA damage in human lymphocytes and lymphoblastoid cells}, author={Idania Rodeiro and René Delgado and Gabino Garrido}, journal={Cell Proliferation}, year={2014}, volume={47}, url={https://api.semanticscholar.org/CorpusID:42821476} }
DNA damage and protection effects of MSBE and mangiferin on primary human lymphocytes and lymphoblastoid cells are tested.
31 Citations
Mango (Mangifera indica L.): a magnificent plant with cancer preventive and anticancer therapeutic potential
- 2020
Medicine, Environmental Science
A comprehensive and critical evaluation of cancer preventive and anticancer therapeutic potential of M. indica and its phytochemicals with special focus on the cellular and molecular mechanisms of action is presented.
Mangiferin and Cancer: Mechanisms of Action
- 2016
Medicine, Biology
The effect of mangiferin on inflammation, with respect to NFκB, PPARү and the immune system, and oxidative stress, through Nrf2/ARE signalling, ROS elimination and catalase activity are focused on.
Pine polyphenols from Pinus koraiensis prevent injuries induced by gamma radiation in mice
- 2016
Environmental Science, Medicine
Results indicate that PPs are radioprotective promising reagents, and reduce the spleen morphologic injury in mice induced by IR.
Central nervous system activities of extract Mangifera indica L.
- 2020
Medicine, Environmental Science
Evidence of Some Natural Products with Antigenotoxic Effects. Part 1: Fruits and Polysaccharides
- 2017
Biology, Environmental Science
An overview of research conducted on some fruits which are frequently consumed by humans, as well as the analysis of some phytochemicals extracted from fruits and yeasts which have demonstrated antigenotoxic capacity in various tests are presented.
Acute and 28-day subchronic toxicity studies of mangiferin, a glucosylxanthone isolated from Mangifera indica L. stem bark
- 2015
Medicine, Environmental Science
These studies indicated that acute and subchronic toxicities of mangiferin for oral exposure are low, suggesting that exocrine pancreas was the target organ for mangiferIn’s toxicity.
Mangifera indica L. stem bark used in the bioinspired formation of silver nanoparticles: catalytic and antibacterial applications
- 2023
Chemistry, Materials Science
This study reports the use of aqueous mango stem bark extract (MSBE) as a source of a relatively cheap and easily accessible reducing and stabilizing agent for the biosynthesis of silver…
Medicinally important aromatic plants with radioprotective activity
- 2017
Medicine, Environmental Science
The present review focuses on a subset of medicinally important aromatic plants with radioprotective activity, mainly exploited for essential oil extraction for applications in industries, for example, in cosmetics, flavoring and fragrance, spices, pesticides, repellents and herbal beverages.
Phytochemical study and evaluation of cytotoxicity, mutagenicity, cell cycle kinetics and gene expression of Bauhinia holophylla (Bong.) Steud. in HepG2 cells in vitro
- 2017
Medicine, Environmental Science
The results of the present study suggest that B. holophylla has potential for use soon as herbal medicine, as well as absence of cytotoxic and mutagenic effects and protective effects against known carcinogens suggest.
54 References
Evaluation of the in vitro antioxidant activity of Mangifera indica L. extract (Vimang)
- 2000
Environmental Science, Medicine
An extract of Mangifera indica L. (Vimang) was tested in vitro for its antioxidant activity using commonly accepted assays. It showed a powerful scavenger activity of hydroxyl radicals and…
An aqueous stem bark extract of Mangifera indica (Vimang®) inhibits T cell proliferation and TNF‐induced activation of nuclear transcription factor NF‐κB
- 2005
Medicine, Environmental Science
A stem bark extract of M. indica inhibits early and late events in T cell activation, including CD25 cell surface expression, progression to the S‐phase of the cell cycle and proliferation in response to T cell receptor (TCR) stimulation.
Mangifera indica L. extract (Vimang) and mangiferin reduce the airway inflammation and Th2 cytokines in murine model of allergic asthma
- 2011
Medicine, Environmental Science
Objectives The aim was to study the effects of Mangifera indica extract and its major component mangiferin on lung inflammation response and Th2 cytokine production using a murine experimental model…
Scavenger effect of a mango (Mangifera indica L.) food supplement’s active ingredient on free radicals produced by human polymorphonuclear cells and hypoxanthine–xanthine oxidase chemiluminescence systems
- 2008
Medicine, Environmental Science
Evaluation of genotoxicity and DNA protective effects of mangiferin, a glucosylxanthone isolated from Mangifera indica L. stem bark extract.
- 2012
Biology, Environmental Science
Evaluation of the genotoxic potential of Mangifera indica L. extract (Vimang), a new natural product with antioxidant activity.
- 2006
Biology, Environmental Science
In vivo and in vitro anti-inflammatory activity of Mangifera indica L . extract ( VIMANG ® )
- 2004
Medicine, Environmental Science
A standard aqueous extract of Mangifera indicaL., used in Cuba as an antioxidant under the brand name of VIMANG ®, was tested in vivo for its anti-inflammatory activity using commonly accepted…
PREVENTING HEPATOCYTE OXIDATIVE STRESS CYTOTOXICITY WITH Mangifera indica L. EXTRACT (VIMANG)
- 2005
Environmental Science, Medicine
This is the first report of cytoprotective antioxidant effects of Vimang in cellular oxidative stress models and the superoxide radical scavenging and antioxidant activity of the Vimang extract was likely related to its gallates, catechins and mangiferin content.
In vivo acute toxicological studies of an antioxidant extract from Mangifera indica L. (Vimang)
- 2009
Environmental Science, Medicine
A toxicological analysis of a standard extract of Mangifera indica stem bark aqueous extract showed that it was nonirritating on skin, ocular, or rectal mucosa and had minimal irritancy following vaginal application.
Effect of Mangifera indica L. extract (QF808) on protein and hepatic microsome peroxidation
- 2001
Environmental Science, Medicine
Results suggest that QF808 has an antioxidant activity, probably due to its ability to scavenge free radicals involved in microsome lipid peroxidation, and its antioxidant profile in vitro is probably similar to its principal polyphenolic component, mangiferin, a glycosylated xanthone.