Effects of a Flaxseed-Derived Lignan Supplement in Type 2 Diabetic Patients: A Randomized, Double-Blind, Cross-Over Trial

@article{Pan2007EffectsOA,
  title={Effects of a Flaxseed-Derived Lignan Supplement in Type 2 Diabetic Patients: A Randomized, Double-Blind, Cross-Over Trial},
  author={An Qiang Pan and Jianqin Sun and Yanqiu Chen and Xingwang Ye and Huaixing Li and Zhijie Yu and Yanfang Wang and Wenjia Gu and Xinyi Cindy Zhang and Xiafei Chen and Wendy Demark-Wahnefried and Yong Liu and Xu Lin},
  journal={PLoS ONE},
  year={2007},
  volume={2},
  pages={1414 - 1431}
}
BACKGROUND Flaxseed consumption has been shown to improve blood lipids in humans and flaxseed-derived lignan has been shown to enhance glycemic control in animals. The study aimed to investigate the effect of a flaxseed-derived lignan supplement on glycemic control, lipid profiles and insulin sensitivity in type 2 diabetic patients. METHODOLOGY/PRINCIPAL FINDINGS This was a randomized, double-blind, placebo-controlled, cross-over trial and it was conducted between April and December 2006 in… CONTINUE READING

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