Effects of a 14-day healthy longevity lifestyle program on cognition and brain function.

@article{Small2006EffectsOA,
  title={Effects of a 14-day healthy longevity lifestyle program on cognition and brain function.},
  author={Gary W. Small and Daniel Silverman and Prabha Siddarth and Linda M. Ercoli and Karen J. Miller and Helen Lavretsky and Benjamin C Wright and Susan Y. Bookheimer and Jorge R. Barrio and Michael E. Phelps},
  journal={The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year={2006},
  volume={14 6},
  pages={
          538-45
        }
}
  • G. Small, Daniel Silverman, +7 authors M. Phelps
  • Published 1 June 2006
  • Psychology, Medicine
  • The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
OBJECTIVE The objective of this study was to determine the effects of a 14-day healthy longevity lifestyle program on cognition and cerebral metabolism in people with mild age-related memory complaints. METHODS Seventeen nondemented subjects, aged 35-69 years (mean: 53 years, standard deviation: 10) with mild self-reported memory complaints but normal baseline memory performance scores were randomly assigned to 1) the intervention group (N = 8): a program combining a brain healthy diet plan… 
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159 Citations
Highly Influential Citations
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Background Citations
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Methods Citations
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Results Citations
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159 Citations

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Citation Type

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  • Psychology
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
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For those with lower education, engaging frequently in cognitive activities showed significant compensatory benefits for episodic memory, which has promise for reducing social disparities in cognitive aging.
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Persistent engagement in PA may have beneficial effects on psychomotor processing speed and brain activation, even for moderate levels and even when started late in life.
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The findings indicate a relation between amount of physical activity and the effects of a cognitive stimulation intervention on perceived cognitive functioning and life satisfaction, and Physically more active persons may gain more benefit from cognitive stimulation than the physically less active.
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Over a 10 week period, increasing frequency of aerobic activity was shown to be associated with enhanced cognitive performance, in particular cognitive flexibility, a measure of executive function.
A pilot study of the effects of meditation on regional brain metabolism in distressed dementia caregivers.
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Meditation practice in distressed caregivers resulted in different patterns of regional cerebral metabolism from relaxation, which should be replicated in a larger study.
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