Effects of a 120 day period of bed-rest on bone mass and bone cell activities in man: attempts at countermeasure.

@article{Vico1987EffectsOA,
  title={Effects of a 120 day period of bed-rest on bone mass and bone cell activities in man: attempts at countermeasure.},
  author={Laurence Vico and Daniel Chappard and Christian Alexandre and Sabine Palle and P M Minaire and G V Riffat and Boris V. Morukov and Sh R Rakhmanov},
  journal={Bone and mineral},
  year={1987},
  volume={2 5},
  pages={383-94}
}
The effects of immobilization on bone mass and bone remodeling in patients with spinal cord injuries are known to simulate weightlessness-induced bone changes in astronauts. Nevertheless, immobilization has never been investigated using histomorphometric studies in healthy volunteers. Twenty healthy male volunteers participated in a '120 day bed-rest' experiment in the USSR. Bone biopsy cores of iliac crest were taken before and at the end of the period of bed-rest. The subjects were divided… CONTINUE READING
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