Effects of Zn(II) binding and apoprotein structural stability on the conformation change of designed antennafinger proteins.

Abstract

Ligand-induced conformation change is a general strategy for controlling protein function. In this work, we demonstrate the relationships between ligand binding and conformational stability using a previously designed protein, Ant-F, which undergoes a conformation change upon Zn(II) binding. To investigate the effect of stabilization of the apo structure on… (More)

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Cite this paper

@article{Hori2004EffectsOZ, title={Effects of Zn(II) binding and apoprotein structural stability on the conformation change of designed antennafinger proteins.}, author={Yuichiro Hori and Yukio Sugiura}, journal={Biochemistry}, year={2004}, volume={43 11}, pages={3068-74} }