Effects of Xiaoqinglong decoction on gene expression profiles in a rat chronic obstructive pulmonary disease model.

@article{Zhang2012EffectsOX,
  title={Effects of Xiaoqinglong decoction on gene expression profiles in a rat chronic obstructive pulmonary disease model.},
  author={Caiqing Zhang and Lili Feng and Ming Wen Li and Chongjuan Dong and Wei Zhang},
  journal={Bioscience trends},
  year={2012},
  volume={6 5},
  pages={
          262-9
        }
}
Xiaoqinglong decoction (XQLD) has been used for centuries in Asia to effectively treat patients with chronic obstructive pulmonary disease (COPD). However, its mechanisms remain unknown. To elucidate this problem, we analyzed the effects of XQLD on gene expressions profiles in COPD rats. In the study, 20 male Wistar rats were injected with lipopolysaccharide (LPS), exposed to cigarette smoke and kept at -20°C for 5 min/day for a successive 8 days to establish COPD animals. Trachea… CONTINUE READING

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