Effects of UV on the migration and function of epidermal antigen presenting cells.

@article{Dandie1998EffectsOU,
  title={Effects of UV on the migration and function of epidermal antigen presenting cells.},
  author={Geoffrey W Dandie and G J Clydesdale and Ian Jacobs and Hans Konrad Muller},
  journal={Mutation research},
  year={1998},
  volume={422 1},
  pages={147-54}
}
Depletion of epidermal Langerhans cells (LC) and the concomitant depression of the skin immune system after excessive exposure to ultraviolet B light (UVB) has been established in the international literature for some time. Our investigations were intended to determine whether or not these phenomena occurred as a direct result of increased LC migration being triggered by the UVB exposure. To test this hypothesis, a sheep model was established in which the lymphatic vessels draining a defined… CONTINUE READING