Effects of Teratogenic Drugs on CYP1A1 Activity in Differentiating Rat Embryo Cells.

Abstract

CYP1A1, a P450 isoenzyme, is involved in the phase I xenobiotic metabolism including teratogen drugs. In the present study, the ability of teratogens to elevate the embryonic expression of CYP1A1 was examined. Micromass cell cultures prepared from day 13 rat embryo limb buds (LB). LB cells were cultivated and exposed for 5 days to retinoic acid (RA… (More)
DOI: 10.1055/s-0034-1370966

Topics

3 Figures and Tables

Cite this paper

@article{Tayeboon2015EffectsOT, title={Effects of Teratogenic Drugs on CYP1A1 Activity in Differentiating Rat Embryo Cells.}, author={Gh S Tayeboon and S. N. Ostad and S Nasri and Amir Nili-Ahmadabadi and Fatemeh Tavakoli and Omid Sabzevari}, journal={Drug research}, year={2015}, volume={65 5}, pages={238-43} }