Effects of TNF-alpha neutralization on adipocytokines and skeletal muscle adiposity in the metabolic syndrome.

@article{Lo2007EffectsOT,
  title={Effects of TNF-alpha neutralization on adipocytokines and skeletal muscle adiposity in the metabolic syndrome.},
  author={Janet Lo and L Elizabeth Bernstein and Bridget Canavan and Martin P Torriani and Malaka B. Jackson and Rexford S. Ahima and Steven K Grinspoon},
  journal={American journal of physiology. Endocrinology and metabolism},
  year={2007},
  volume={293 1},
  pages={E102-9}
}
In a prior study, we have shown that tumor necrosis factor (TNF)-alpha neutralization improves inflammatory markers and total adiponectin in patients with the metabolic syndrome, without improving insulin sensitivity. In this study, we sought to extend our understanding of the effects of TNF-alpha neutralization in this human model of obesity by investigating the responses of high-molecular-weight (HMW) adiponectin, resistin, leptin, and muscle adiposity to etanercept in patients with the… CONTINUE READING
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Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in E107 TNF- NEUTRALIZATION AND ADIPOCYTOKINES AJP-Endocrinol Metab

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  • Jne 25,
  • 2007
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