Effects of Stem Cell Factor on the Growth and Radiation Survival of Tumor Cells 1

Abstract

Recombinant human stem cell factor (SCF) binds to the c-kit receptor on human bone marrow progenitor cells and enhances their survival following irradiation. Since the c-kil receptor has also been detected on malignant cells, experiments were performed to study the effect of SCF on the proliferation and radiation survival of a variety of both c-foY-positive… (More)

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