Effects of Splenectomy on Spontaneously Chronic Pancreatitis in aly/aly Mice

Abstract

BACKGROUND AND AIM Mice with alymphoplasia (aly/aly) mutation characterized by a lack of lymph nodes, Peyer's patches, and well-defined lymphoid follicles in the spleen were found. In this study, we used splenectomized aly/aly mice to elucidate the effects of secondary lymphoid organs in the development of aly/aly autoimmune pancreatitis. METHODS Forty… (More)
DOI: 10.1155/2010/614890

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