Corpus ID: 11700980

Effects of Sperm Chromatin Integrity on Fertilization Rate and Embryo Quality Following Intracytoplasmic Sperm Injection

@article{Sadeghi2009EffectsOS,
  title={Effects of Sperm Chromatin Integrity on Fertilization Rate and Embryo Quality Following Intracytoplasmic Sperm Injection},
  author={M. Sadeghi and M. Hodjat and N. Lakpour and S. Arefi and N. Amirjannati and T. Modarresi and Hossain Hossaini Jadda and M. Akhondi},
  journal={Avicenna Journal of Medical Biotechnology},
  year={2009},
  volume={1},
  pages={173 - 180}
}
Sperm chromatin integrity has been being recognized as an important factor in male fertility. During normal fertilization, high quality sperm with intact chromatin are selected through natural selection in journey from vagina to fallopian tube. However, using Assisted Reproductive Techniques, particularly ICSI, the natural selection is bypassed. Therefore sperm with DNA breakage have the opportunity to fertilize the egg which may lead to decreased embryo quality and implantation rate. The aim… Expand
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