Effects of Smilaxchinoside A and Smilaxchinoside C, Two Steroidal Glycosides from Smilax riparia, on Hyperuricemia in a Mouse Model

  title={Effects of Smilaxchinoside A and Smilaxchinoside C, Two Steroidal Glycosides from Smilax riparia, on Hyperuricemia in a Mouse Model},
  author={Xiao-hui Wu and Chong-Zhi Wang and Jun Zhang and Shu-Qing Wang and Lide Han and Yan-Wen Zhang and Chun-Su Yuan},
  journal={Phytotherapy Research},
  pages={1822 - 1828}
The roots and rhizomes of Smilax riparia, called ‘Niu‐Wei‐Cai’ in traditional Chinese medicine, are believed to be effective in treating the symptoms of gout. However, the active constituents and their uricosuric mechanisms are unknown. In this study, we isolated two steroidal glycosides, named smilaxchinoside A and smilaxchinoside C, from the total saponins obtained from the ethanol extract of the roots of S. riparia. We then examined if these two compounds were effective in reducing serum… 
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