Effects of Silver Nanoparticles on Primary Mixed Neural Cell Cultures: Uptake, Oxidative Stress and Acute Calcium Responses

@inproceedings{Haase2012EffectsOS,
  title={Effects of Silver Nanoparticles on Primary Mixed Neural Cell Cultures: Uptake, Oxidative Stress and Acute Calcium Responses},
  author={Andrea Haase and Stephanie Rott and Alexandre Mantion and Philipp Graf and Johanna Plendl and Andreas F Th{\"u}nemann and Wolfgang Meier and Andreas Taubert and Andreas Luch and Georg Reiser},
  booktitle={Toxicological sciences : an official journal of the Society of Toxicology},
  year={2012}
}
In the body, nanoparticles can be systemically distributed and then may affect secondary target organs, such as the central nervous system (CNS). Putative adverse effects on the CNS are rarely investigated to date. Here, we used a mixed primary cell model consisting mainly of neurons and astrocytes and a minor proportion of oligodendrocytes to analyze the effects of well-characterized 20 and 40 nm silver nanoparticles (SNP). Similar gold nanoparticles served as control and proved inert for all… CONTINUE READING
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The inhibitory effects of nano - Ag on voltage - gated potassium currents of hippocampal CA 1 neurons

  • T. Zhang, Z. Yang
  • Environ . Toxicol .
  • 2011

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