Effects of Sho-saiko-to extract and its components, Baicalin, baicalein, glycyrrhizin and glycyrrhetic acid, on pharmacokinetic behavior of salicylamide in carbon tetrachloride intoxicated rats.

@article{Taira2004EffectsOS,
  title={Effects of Sho-saiko-to extract and its components, Baicalin, baicalein, glycyrrhizin and glycyrrhetic acid, on pharmacokinetic behavior of salicylamide in carbon tetrachloride intoxicated rats.},
  author={Zenei Taira and Kazunori Yabe and Yuka Hamaguchi and Kensuke Hirayama and Makoto Kishimoto and Shiro Ishida and Yukari Ueda},
  journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  year={2004},
  volume={42 5},
  pages={803-7}
}
To elucidate the effects of Sho-saiko-to extract and its components, baicalin, baicalein, glycyrrhizin and glycyrrhetic acid, against the effects of longer periods of acute hepatic injury induced by CCl4, we measured serum ALT activity in male Wistar rats for five days after ip administration of CCl4 (0.2 ml/kg), and examined the daily changes of the… CONTINUE READING