Effects of Severe Hypoxia on Bone Marrow Mesenchymal Stem Cells Differentiation Potential

@inproceedings{Cicione2013EffectsOS,
  title={Effects of Severe Hypoxia on Bone Marrow Mesenchymal Stem Cells Differentiation Potential},
  author={Claudia Cicione and Emma Mui{\~n}os-L{\'o}pez and Tamara Hermida-G{\'o}mez and Isaac Manuel Fuentes-Boquete and Silvia Mar{\'i}a D{\'i}az-Prado and Francisco J Blanco},
  booktitle={Stem cells international},
  year={2013}
}
Background. The interests in mesenchymal stem cells (MSCs) and their application in cell therapy have resulted in a better understanding of the basic biology of these cells. Recently hypoxia has been indicated as crucial for complete chondrogenesis. We aimed at analyzing bone marrow MSCs (BM-MSCs) differentiation capacity under normoxic and severe hypoxic culture conditions. Methods. MSCs were characterized by flow cytometry and differentiated towards adipocytes, osteoblasts, and chondrocytes… CONTINUE READING

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