Effects of Selective Activation of M1 and M4 Muscarinic Receptors on Object Recognition Memory Performance in Rats

@article{Galloway2014EffectsOS,
  title={Effects of Selective Activation of M1 and M4 Muscarinic Receptors on Object Recognition Memory Performance in Rats},
  author={Claire R. Galloway and E. Lebois and Shezza L Shagarabi and N. A. Hern{\'a}ndez and J. Manns},
  journal={Pharmacology},
  year={2014},
  volume={93},
  pages={57 - 64}
}
Acetylcholine signaling through muscarinic receptors has been shown to benefit memory performance in some conditions, but pan-muscarinic activation also frequently leads to peripheral side effects. Drug therapies that selectively target M1 or M4 muscarinic receptors could potentially improve memory while minimizing side effects mediated by the other muscarinic receptor subtypes. The ability of three recently developed drugs that selectively activate M1 or M4 receptors to improve recognition… Expand
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