Effects of SCH-23390 on dopamine D1 receptor occupancy and locomotion produced by intraaccumbens cocaine infusion.

@article{Neisewander1998EffectsOS,
  title={Effects of SCH-23390 on dopamine D1 receptor occupancy and locomotion produced by intraaccumbens cocaine infusion.},
  author={Janet L. Neisewander and Rita A. Fuchs and Laura E O'Dell and Taline V. Khroyan},
  journal={Synapse},
  year={1998},
  volume={30 2},
  pages={
          194-204
        }
}
  • Janet L. Neisewander, Rita A. Fuchs, +1 author Taline V. Khroyan
  • Published in Synapse 1998
  • Psychology, Medicine
  • This study examined the effects of both systemic and intraaccumbens administration of SCH-23390 in rats on dopamine D1 receptor occupancy and on locomotor activity produced by intraaccumbens infusion of cocaine. In experiment 1, rats received SCH-23390 (0-1 mg/kg, i.p.) 15 minutes prior to intraaccumbens infusion of cocaine (0 or 100 microg/side). In experiment 2, rats received coinfusion of SCH-23390 (0-1 microg/side) and cocaine (0 or 100 microg/side) into the nucleus accumbens (NAc). After… CONTINUE READING

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