Effects of Renin-Angiotensin System Inhibitors on Renal Expression of Renalase in Sprague-Dawley Rats Fed With High Salt Diet

@article{Wang2015EffectsOR,
  title={Effects of Renin-Angiotensin System Inhibitors on Renal Expression of Renalase in Sprague-Dawley Rats Fed With High Salt Diet},
  author={Yuhuai Wang and Bing-Qing Xie and Wei-hua Gao and Ding-Yi Yan and Wen-ling Zheng and Yong-Bo Lv and Yu-Meng Cao and Jia-Wen Hu and Zu-Yi Yuan and Jian-jun Mu},
  journal={Kidney and Blood Pressure Research},
  year={2015},
  volume={40},
  pages={605 - 613}
}
Background/Aims: The aim of our study was to investigate the effect of high-salt diet on the renal expression of renalase and the potential role of the local renin-angiotensin system in this process. Methods: Sprague-Dawley (SD) rats were divided into groups according to salt content in diet and drug treatment as follows: normal-salt diet (NS), high-salt diet (HS), high-salt intake with hydralazine (HS+H), high-salt diet with enalapril (HS+E), and high-salt diet with valsartan (HS+V). The… CONTINUE READING

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