Effects of Remifemin Treatment on Bone Integrity and Remodeling in Rats with Ovariectomy-Induced Osteoporosis

Abstract

This study aims to evaluate the effects of Remifemin (isopropanolic extract of Cimicifuga Racemosa) on postmenopausal osteoporosis. 120 female Sprague-Dawley rats were randomly assigned to four groups: sham surgery with vehicle, ovariectomy with vehicle, ovariectomy with estradiol valerate, or ovariectomy with Remifemin. Daily oral administrations of the… (More)
DOI: 10.1371/journal.pone.0082815

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@inproceedings{Cui2013EffectsOR, title={Effects of Remifemin Treatment on Bone Integrity and Remodeling in Rats with Ovariectomy-Induced Osteoporosis}, author={Guangxia Cui and Huijie Leng and Ke Wang and Jianwei Wang and Sainan Zhu and Jing Jia and Xing Chen and Weiguang Zhang and Li-hua Qin and Wenpei Bai}, booktitle={PloS one}, year={2013} }