Effects of REM sleep deprivation of ACTH-induced yawning.


Central administration of ACTH in rats induces yawning and stretching. In order to study the effects of REM sleep deprivation on ACTH-induced yawning, the peptide was injected immediately after the REM sleep deprivation period or 24 h later. REM sleep deprivation impaired ACTH-induced yawning, but after a 24-hour recovery period, rats displayed a number of yawns similar to those in control animals. Implications for an involvement of dopaminergic and mainly cholinergic systems are discussed.

Cite this paper

@article{Lobo1990EffectsOR, title={Effects of REM sleep deprivation of ACTH-induced yawning.}, author={Lu{\'i}sa Lobo and Bastian Neumann and D S Eidman and Sergio Brasil Tufik}, journal={Pharmacology}, year={1990}, volume={40 3}, pages={174-8} }