Effects of Quetiapine on Sleep in Nonpsychiatric and Psychiatric Conditions

@article{Wine2009EffectsOQ,
  title={Effects of Quetiapine on Sleep in Nonpsychiatric and Psychiatric Conditions},
  author={Jesse Wine and Cristina Sanda and Joshua Caballero},
  journal={Annals of Pharmacotherapy},
  year={2009},
  volume={43},
  pages={707 - 713}
}
Objective: To evaluate the use of immediate-release quetiapine for the treatment of insomnia. Data Sources: Pre-MEDLINE and MEDLINE were searched (1966 to October 2008) using the terms quetiapine, sleep, insomnia, and antipsychotics. Study Selection and Data Extraction: All studies and case reports evaluating insomnia as a primary endpoint were reviewed. Data Synthesis: The role of quetiapine for improving sleep in various patient populations is uncertain. Quetiapine has moderately sedative… 
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It is suggested that quetiapine may be a safe and effective treatment of insomnia in PD patients and double-blind studies will probably confirm these findings.
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The sleep-improving properties of quetiapine may be important in counteracting different aspects of psychopathology in schizophrenia and other disorders and other mechanisms might be relevant as well and further investigation is required.
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TLDR
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TLDR
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