Effects of Psilocybe argentipes on Marble-Burying Behavior in Mice

@article{Matsushima2009EffectsOP,
  title={Effects of Psilocybe argentipes on Marble-Burying Behavior in Mice},
  author={Yoshihiro Matsushima and Osamu Shirota and Ruri Kikura-Hanajiri and Yukihiro Goda and Fumio Eguchi},
  journal={Bioscience, Biotechnology, and Biochemistry},
  year={2009},
  volume={73},
  pages={1866 - 1868}
}
Psilocybe argentipes is a hallucinogenic mushroom. The present study examined the effects of P. argentipes on marble-burying behavior, which is considered an animal model of obsessive-compulsive disorder. P. argentipes significantly inhibited marble-burying behavior without affecting locomotor activity as compared with the same dose of authentic psilocybin. These findings suggest that P. argentipes would be efficient in clinical obsessive-compulsive disorder therapy. 
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