Effects of Pro-Gly-Pro Tripeptide on the Dopamine System


Tripeptide Pro-Gly-Pro interacted with dopamine receptors in vitro and reduced behavioral manifestations of apomorphine-induced hyperfunction of the dopamine system in verticalization, stereotypy, and yawning tests. Presumably, the behavioral effects of Pro-Gly-Pro tripeptide were mediated through post- and presynaptic D2 and D3 receptors.

DOI: 10.1007/s10517-011-1348-2

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@article{Meshavkin2011EffectsOP, title={Effects of Pro-Gly-Pro Tripeptide on the Dopamine System}, author={Viktor Meshavkin and E. Yu. Batishcheva and Natalya Kost and Olexandr Sokolov and A. V. Trufanova and G. E. Samonina}, journal={Bulletin of Experimental Biology and Medicine}, year={2011}, volume={151}, pages={429-431} }