Effects of Peroxisome Proliferator-Activated Receptor Ligand and Brown Seaweed Based Compound on Megakaryocyte

@article{Choi2019EffectsOP,
  title={Effects of Peroxisome Proliferator-Activated Receptor Ligand and Brown Seaweed Based Compound on Megakaryocyte},
  author={Jae-Lim Choi and Ri-Young Goh and Seong-Hoon Yun and Joo-In Park and Jin-Yeong Han},
  journal={Clinical \& Experimental Thrombosis and Hemostasis},
  year={2019}
}
Platelets are anuclear cells released from megakaryocytes, the rare myeloid cells that undergo multiple rounds of endomitosis before releasing platelets. Platelets, known as the mediator of thrombosis, are emerging as cellular mediators of type II diabetes, atherosclerosis, cancer cell metastasis, and immune responses. Despite the lack of a nucleus, they express a large number of transcription factors including peroxisome proliferator-activated receptor (PPAR). PPAR needs ligand-binding to be… Expand

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