Effects of Perfluorocarbons on surfactant exocytosis and membrane properties in isolated alveolar type II cells

@inproceedings{Wemhner2010EffectsOP,
  title={Effects of Perfluorocarbons on surfactant exocytosis and membrane properties in isolated alveolar type II cells},
  author={Andreas Wemh{\"o}ner and Irmgard Hackspiel and Nina Hobi and Andrea Ravasio and Thomas Haller and Mario Ruediger},
  booktitle={Respiratory research},
  year={2010}
}
BackgroundPerfluorocarbons (PFC) are used to improve gas exchange in diseased lungs. PFC have been shown to affect various cell types. Thus, effects on alveolar type II (ATII) cells and surfactant metabolism can be expected, data, however, are controversial.ObjectiveThe study was performed to test two hypotheses: (I) the effects of PFC on surfactant exocytosis depend on their respective vapor pressures; (II) different pathways of surfactant exocytosis are affected differently by PFC… CONTINUE READING

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