Effects of PDGF-C and PDGF-D on monocyte migration and MMP-2 and MMP-9 expression.

@article{Wgster2009EffectsOP,
  title={Effects of PDGF-C and PDGF-D on monocyte migration and MMP-2 and MMP-9 expression.},
  author={Dick W{\aa}gs{\"a}ter and Chaoyong Zhu and Hanna M. Bj{\"o}rck and Per Eriksson},
  journal={Atherosclerosis},
  year={2009},
  volume={202 2},
  pages={415-23}
}
BACKGROUND AND AIMS Atherosclerosis is a chronic inflammatory process involving the activity of several cytokines and growth factors. Platelet-derived growth factor-A (PDGF-A) and PDGF-B are important mitogens and chemoattractants for monocytes as well as smooth muscle cells. We sought to identify the role of PDGF-C and PDGF-D, two new members of the PDGF family, in monocyte migration and differentiation. We also assessed their effects in regulating matrix metalloproteinase-2 (MMP-2) and MMP-9… CONTINUE READING