Effects of PACAP on Mitochondrial Apoptotic Pathways and Cytokine Expression in Rats Subjected to Renal Ischemia/Reperfusion

@article{Horvath2010EffectsOP,
  title={Effects of PACAP on Mitochondrial Apoptotic Pathways and Cytokine Expression in Rats Subjected to Renal Ischemia/Reperfusion},
  author={Gabriella Horvath and B{\'o}gl{\'a}rka R{\'a}cz and Dora Reglodi and Krisztina {\'E}va Kov{\'a}cs and P{\'e}ter Kiss and F. erenc Gallyas and Zita Bognar and Aliz Szabo and Tam{\'a}s Magyarlaki and Eszter L{\'a}szl{\'o} and Andrea Pethőn{\'e} dr. Lubics and Andrea Tamas and Gabor X Toth and P{\'e}ter Szak{\'a}ly},
  journal={Journal of Molecular Neuroscience},
  year={2010},
  volume={42},
  pages={411-418}
}
Pituitary adenylate cyclase activating polypeptide (PACAP) is a neuropeptide with highly efficient cytoprotective actions. Its neuroprotective effects are well-known, but PACAP is able to exert similar actions in non-neuronal cells. Recently, we have shown that PACAP prolongs renal ischemic time, decreases mortality, and attenuates tubular degeneration in a rat model of renal ischemia/reperfusion, but the mechanism of renoprotection is not yet known. Therefore, the aim of the present study was… CONTINUE READING
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Evaluation of the protective

  • K Szabadfi, P Kiss
  • 2010

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