Corpus ID: 51004543

Effects of Oral Glucosamine and Chondroitin Sulfates Supplementation on Frequency of Intra-articular Therapy of the Horse Tarsus

@inproceedings{Rodgers2006EffectsOO,
  title={Effects of Oral Glucosamine and Chondroitin Sulfates Supplementation on Frequency of Intra-articular Therapy of the Horse Tarsus},
  author={Martha R. Rodgers},
  year={2006}
}
Effects of oral glucosamine/chondroitin (Glu/Chon) sulfates supplementation on the frequency of intra-articular injection of the distal intertarsal joints (distal intertarsal [DIT] and tarsometatarsal [TMT]) were evaluated in 10 horses used as competitive hunter/jumpers. Study duration was 8 years—2 years before supplementation and 6 years of supplementation (10 g active Glu/Chon daily). Clinical lameness evaluations (palpation and flexion tests), radiographs, and intra-articular anesthesia or… Expand
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References

SHOWING 1-10 OF 103 REFERENCES
Glucosamine sulphate for the management of arthrosis: a controlled clinical investigation.
TLDR
A new preparation of pure glucosamine sulphate, in injectable and oral form, was investigated in a controlled clinical trial in patients with osteoarthrosis, and each symptom significantly improved. Expand
Glucosamine sulphate: a controlled clinical investigation in arthrosis.
TLDR
It is suggested that parenteral and/or oral treatment with pure glucosamine sulphate should be considered as basic therapy for the management of primary or secondary degenerative osteoarthrosis disorders. Expand
Glucosamine, chondroitin, and manganese ascorbate for degenerative joint disease of the knee or low back: a randomized, double-blind, placebo-controlled pilot study.
TLDR
The combination therapy relieves symptoms of knee osteoarthritis and appears safe in this setting and a larger data set is needed to determine the value of this therapy for spinal DJD. Expand
Effects of oral chondroitin sulfate on the progression of knee osteoarthritis: a pilot study.
TLDR
It is confirmed that oral chondroitin 4- and 6-sulfate is an effective and safe symptomatic slow-acting drug for the treatment of knee OA and CS might be able to stabilize the joint space width and to modulate bone and joint metabolism. Expand
Oral treatment with a glucosamine-chondroitin sulfate compound for degenerative joint disease in horses: 25 cases
TLDR
Tarek A. Hammad, MD, PhD, Msc, MS Department of Epidemiology University of Maryland School of Medicine Baltimore, Maryland explains why traditional treatment of DJD has centered around non steroidal anti-inflammatory drugs (NSAIDs) and steroidalAnti-inflammatory agents. Expand
Safety of an oral chondroprotective agent in horses.
TLDR
The results of this study suggest that the oral chondroprotective agent tested is safe for administration to horses at recommended dose rates. Expand
Oral treatment with a nutraceutical (Cosequin) for ameliorating signs of navicular syndrome in horses.
TLDR
The median algofunctional lameness index and overall clinical condition scores assigned by owners after 8 weeks were significantly improved for horses treated with the nutraceutical compared with placebo-treated horses. Expand
Glucosamine sulfate compared to ibuprofen in osteoarthritis of the knee.
TLDR
Glucosamine sulfate was therefore as effective as ibuprofen on symptoms of knee OA and is confirmed as a safe symptomatic Slow Acting Drug for OA. Expand
The role of glucosamine sulfate and chondroitin sulfates in the treatment of degenerative joint disease.
  • G. Kelly
  • Chemistry, Medicine
  • Alternative medicine review : a journal of clinical therapeutic
  • 1998
TLDR
Evidence supports the oral administration of chondroitin sulfates for joint disease, both as an agent to slowly reduce symptoms and to reduce the need for non-steroidal anti-inflammatory drugs. Expand
Double-blind clinical evaluation of oral glucosamine sulphate in the basic treatment of osteoarthrosis.
TLDR
The efficacy and tolerance of oral glucosamine sulphate were tested against placebo in a prospective double-blind trial in 20 out-patients with established osteoarthrosis and significant alleviation of symptoms was associated with the use of the active drug at the prescribed dose. Expand
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3
4
5
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