Effects of OSA, inhalational anesthesia, and fentanyl on the airway and ventilation of children.

@article{Waters2002EffectsOO,
  title={Effects of OSA, inhalational anesthesia, and fentanyl on the airway and ventilation of children.},
  author={Karen A Waters and Fergus McBrien and Penny Stewart and Murray Hinder and Sally Wharton},
  journal={Journal of applied physiology},
  year={2002},
  volume={92 5},
  pages={1987-94}
}
To assess effects of anesthesia and opioids, we studied 13 children with obstructive sleep apnea (OSA, age 4.0 +/- 2.2 yr, mean +/- SD) and 24 age-matched control subjects (5.8 +/- 4.0 yr). Apnea indexes of children with OSA were 29.4 +/- 18 h-1, median 30 h-1. Under inhalational anesthetic, closing pressure at the mask was 2.2 +/- 6.9 vs. -14.7 +/- 7.8 cmH2O, OSA vs. control (P < 0.001). After intubation, spontaneous ventilation was 115.5 +/- 56.9 vs. 158.7 +/- 81.6 ml x kg-1 small middle dot… CONTINUE READING