In fiscal 1974 and fiscal 1975, $650000 will be spent on contracts for studies of birth control methods and their relationship to birth defects. The effect of oral contraceptives (OCs) on various nutrients is among top interest. It has been shown that OCs increase blood levels of Vitamin-A, copper and iron while they decrease folic acid, zinc and Vitamin-B12 and B6. The decrease of Vitamin-B6 interfers with the tryptophan mechanism and affects glucose tolerance as well as neurotransmitters which can be directly related to reports of depression and a higher rate of bladder cancer. A question arose as to whether dietary supplements would counteract the nutritional depletion. The group of unanswered questions was summed up by a question: "So, the question is, is it the pill or the pill user?"