Effects of N-propargyl-1-(R)aminoindan (rasagiline) in models of motor and cognition disorders.

  title={Effects of N-propargyl-1-(R)aminoindan (rasagiline) in models of motor and cognition disorders.},
  author={Zipora Speiser and Ross Levy and Samia Cohen},
  journal={Journal of neural transmission. Supplementum},
N-propargyl-1-(R)aminoindan (rasagiline) is a new and selective irreversible MAO-B inhibitor, currently being considered as the mesylate salt for potential therapy in certain neurological disorders. It has been studied in animal models of cognition and motor dysfunction. Its ability to restore normal motor activity was determined in models of acute drug-induced dopaminergic dysfunction: Its effects in improving cognition and memory deficits was studied in adult and senescent rats that had been… CONTINUE READING


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