Effects of N-methyl-d-aspartate antagonism on spatial learning in mice

Abstract

C57BL/6Ibg mice were treated with the N-methyl-d-aspartate (NMDA) receptor antagonist 3-(2-carboxypiperazin-4-yl) propyl-1-phosphonic acid (CPP) and tested for selective deficits in spatial learning ability in the Morris water task. Two types of training protocols were used during the initial exposure to the training environment. In protocol 1, animals were… (More)
DOI: 10.1007/BF02244408

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Cite this paper

@article{Upchurch1990EffectsON, title={Effects of N-methyl-d-aspartate antagonism on spatial learning in mice}, author={Margaret B Upchurch and Jeanne M. Wehner}, journal={Psychopharmacology}, year={1990}, volume={100}, pages={209-214} }