Effects of N-acetylcysteine on cytokines in non-acetaminophen acute liver failure: potential mechanism of improvement in transplant-free survival.

Abstract

BACKGROUND N-Acetylcysteine (NAC) improves transplant-free survival in patients with non-acetaminophen acute liver failure (ALF) when administered in early stages of hepatic encephalopathy. The mechanisms of this benefit are unknown. AIM To determine whether NAC improves transplant-free survival in ALF by ameliorating the surge of pro-inflammatory… (More)
DOI: 10.1111/liv.12214

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