Effects of Moderate and Subsequent Progressive Weight Loss on Metabolic Function and Adipose Tissue Biology in Humans with Obesity.

@article{Magkos2016EffectsOM,
  title={Effects of Moderate and Subsequent Progressive Weight Loss on Metabolic Function and Adipose Tissue Biology in Humans with Obesity.},
  author={Faidon Magkos and Gemma Fraterrigo and Jun Yoshino and Courtney Tiemann Luecking and Kyleigh Kirbach and Shannon C Kelly and Lisa de Las Fuentes and Songbing He and Adewole L Okunade and Bruce W. Patterson and Samuel Klein},
  journal={Cell metabolism},
  year={2016},
  volume={23 4},
  pages={591-601}
}
Although 5%-10% weight loss is routinely recommended for people with obesity, the precise effects of 5% and further weight loss on metabolic health are unclear. We conducted a randomized controlled trial that evaluated the effects of 5.1% ± 0.9% (n = 19), 10.8% ± 1.3% (n = 9), and 16.4% ± 2.1% (n = 9) weight loss and weight maintenance (n = 14) on metabolic outcomes. 5% weight loss improved adipose tissue, liver and muscle insulin sensitivity, and β cell function, without a concomitant change… CONTINUE READING
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Effects of Moderate and Subsequent Progressive Weight Loss on Metabolic Function and Adipose Tissue Biology in Humans with Obesity, Cell Metabolism

  • Magkos
  • 2016

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