Effects of MgADP on length dependence of tension generation in skinned rat cardiac muscle.

Abstract

The effect of MgADP on the sarcomere length (SL) dependence of tension generation was investigated using skinned rat ventricular trabeculae. Increasing SL from 1.9 to 2.3 microm decreased the muscle width by approximately 11% and shifted the midpoint of the pCa-tension relationship (pCa(50)) leftward by about 0.2 pCa units. MgADP (0.1, 1, and 5 mmol/L… (More)

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@article{Fukuda2000EffectsOM, title={Effects of MgADP on length dependence of tension generation in skinned rat cardiac muscle.}, author={Nobuo Fukuda and Hirohisa Kajiwara and Shintaro Ishiwata and Susumu Kurihara}, journal={Circulation research}, year={2000}, volume={86 1}, pages={E1-6} }