• Corpus ID: 55553229

Effects of Methylglyoxal, TNF-α and IL-1α on Proteoglycan Synthesis in Human Endothelial Cells in vitro

  title={Effects of Methylglyoxal, TNF-$\alpha$ and IL-1$\alpha$ on Proteoglycan Synthesis in Human Endothelial Cells in vitro},
  author={Lisa M. Johansen and Svein O Kolset and Katja Svennevig and Annicke Stranda},


Increase in Three α,β-Dicarbonyl Compound Levels in Human Uremic Plasma: Specificin VivoDetermination of Intermediates in Advanced Maillard Reaction
In both diabetic and uremic patients, these dicarbonyl compounds promote AGE accumulation in vivo, and especially in uremi patients, increased accumulation of GO could result from accelerating oxidative stress.
High glucose and Nε-(carboxymethyl) lysine bovine serum albumin modulate release of matrix metalloproteinases in cultured human endothelial cells
The HUVEC exposed to high glucose or AGE exhibit decreased secretion of MMP-2, which may be relevant in understanding the altered turnover of the endothelial extracellular matrix observed in the diabetic state.
Effects of matrix glycation on mesangial cell adhesion, spreading and proliferation.
We examined the effects of in vitro nonenzymatic glycosylation (NEG) of the extracellular matrix (ECM) on various aspects of the adhesive interaction between the ECM and human kidney mesangial (HKM)
Insulin resistance, endocrine function and adipokines in type 2 diabetes patients at different glycaemic levels: potential impact for glucotoxicity in vivo
Objective  To evaluate the interplay between hyperglycaemia, insulin resistance, hormones and adipokines in patients with type 2 diabetes mellitus (T2DM).
Chemokine gene expression and secretion by cytokine-activated human microvascular endothelial cells. Differential regulation of monocyte chemoattractant protein-1 and interleukin-8 in response to interferon-gamma.
The elicitation of leukocytes from the circulation to inflamed tissue depends on the activation of both the leukocyte and endothelial cell. In this study we determined the gene expression and