Effects of Membrane Charge and Order on Membrane Binding of the Retroviral Structural Protein Gag.

Abstract

UNLABELLED The retroviral structural protein Gag binds to the inner leaflet of the plasma membrane (PM), and many cellular proteins do so as well. We used Rous sarcoma virus (RSV) Gag together with membrane sensors to study the principles governing peripheral protein membrane binding, including electrostatics, specific recognition of phospholipid headgroups… (More)
DOI: 10.1128/JVI.01102-16

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