Effects of Melatonin in Perimenopausal and Menopausal Women: Our Personal Experience

@article{Bellipanni2005EffectsOM,
  title={Effects of Melatonin in Perimenopausal and Menopausal Women: Our Personal Experience},
  author={G Bellipanni and Fernando L. Marzo and Federico B M Blasi and Antonio Marzo},
  journal={Annals of the New York Academy of Sciences},
  year={2005},
  volume={1057}
}
The purpose of this clinical trial on possible effects of nocturnal MEL administration in perimenopausal women was to find if MEL by itself modifies levels of hormones and produces changes of any kind, independently of age (42-62 years of age) and the stage of the menstrual cycle. [...] Key Method Subjects took a daily dose of 3 mg synthetic melatonin or a placebo for 6 months. Levels of melatonin were determined from five daily saliva samples taken at fixed times.Expand
The effect of long-term melatonin supplementation on psychosomatic disorders in postmenopausal women.
TLDR
It is concluded that melatonin supplementation therapy exerts a positive effect on psychosomatic symptoms in postmenopausal women and can be recommended as the useful adjuvant therapeutic option in treatment of these disorders.
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Focus is given to melatonin effect on the female reproductive system, its participation in the aging process, and formation of pathological menopause, and research data on the effectiveness of the melatonin drug when tackling climacteric syndrome is presented.
Melatonin in perimenopausal and postmenopausal women: associations with mood, sleep, climacteric symptoms, and quality of life
TLDR
Longitudinal research is needed to better understand the possible contributory role of menopause in lower melatonin levels and to evaluate melatonin’s influence on mood, sleep, vasomotor symptoms, and quality of life.
The effect of melatonin on the sexual function among postmenopausal women: A randomized placebo-controlled trial
TLDR
Melatonin significantly improves sexual function among postmenopausal women and was significantly greater than the control group at all other assessment points.
Melatonin and the health of menopausal women: A systematic review
TLDR
In light of multiple health benefits and an excellent safety profile, melatonin administration should be considered in menopausal women.
Melatonin in perimenopausal and postmenopausal women : associations with mood , 1 sleep , climacteric symptoms and quality of life 2 Running Title : Melatonin in perimenopause and postmenopause 3 4
30 Objective: Melatonin synthesis and secretion are partly modulated by estrogen and 31 progesterone. Changes in melatonin concentrations, possibly related to the menopausal 32 transition, may be
Myo-inositol and melatonin in the menopausal transition
  • R. D'Anna, A. Santamaria, +4 authors S. Benvenga
  • Medicine
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
  • 2017
TLDR
The combination of myo-Ins plus melatonin seems to affect positively glucose metabolism, while myo -Ins only seems to improve thyroid function in women during menopausal transition.
Insomnia and menopause: a narrative review on mechanisms and treatments
TLDR
Cognitive behavioral therapy represents the first-line treatment of insomnia in the general population, regardless of the presence of mood disorders and/or vasomotor symptoms (VMS), and prolonged-released melatonin should represent a first- line drug in women aged ≥ 55 years.
Sleep, Melatonin, and the Menopausal Transition: What Are the Links?
TLDR
The pathophysiology of melatonin function as it relates to sleep disorders in menopausal women is discussed, highlighting the potential use of exogenous melatonin during the menopausal transition and beyond.
The value of melatonin supplementation in postmenopausal women with Helicobacter pylori-associated dyspepsia
TLDR
Melatonin supplementation is useful in treating H. pylori -associated dyspepsia, particularly in postmenopausal women with lower levels of this hormone, and examine the role of Helicobacter infection.
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