Effects of Melatonin in Perimenopausal and Menopausal Women: Our Personal Experience

@article{Bellipanni2005EffectsOM,
  title={Effects of Melatonin in Perimenopausal and Menopausal Women: Our Personal Experience},
  author={G Bellipanni and Fernando L. Marzo and Federico B M Blasi and Antonio Marzo},
  journal={Annals of the New York Academy of Sciences},
  year={2005},
  volume={1057}
}
The purpose of this clinical trial on possible effects of nocturnal MEL administration in perimenopausal women was to find if MEL by itself modifies levels of hormones and produces changes of any kind, independently of age (42-62 years of age) and the stage of the menstrual cycle. [] Key Method Subjects took a daily dose of 3 mg synthetic melatonin or a placebo for 6 months. Levels of melatonin were determined from five daily saliva samples taken at fixed times.
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54 Citations
Highly Influential Citations
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Background Citations
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54 Citations

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It is concluded that melatonin supplementation therapy exerts a positive effect on psychosomatic symptoms in postmenopausal women and can be recommended as the useful adjuvant therapeutic option in treatment of these disorders.

Role of Pineal Hormone Melatonin in a Woman’s Life: From Conception to Decline of Life

Focus is given to melatonin effect on the female reproductive system, its participation in the aging process, and formation of pathological menopause, and research data on the effectiveness of the melatonin drug when tackling climacteric syndrome is presented.

Melatonin in perimenopausal and postmenopausal women: associations with mood, sleep, climacteric symptoms, and quality of life

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Melatonin significantly improves sexual function among postmenopausal women and was significantly greater than the control group at all other assessment points.

Melatonin and the health of menopausal women: A systematic review

In light of multiple health benefits and an excellent safety profile, melatonin administration should be considered in menopausal women.

The features of optimal nonhormonal therapy of vegetative disorders among women with postmenopause

The use of Vitae-Melatonin at a dose of 3 mg/day in addition to phytotherapy in postmenopausal women had a clear clinical effect, which was a significant reduction of vegetative disorders, both compared to the initial indicators and in comparison with monophytotherapy.

Myo-inositol and melatonin in the menopausal transition

  • R. D'AnnaA. Santamaria S. Benvenga
  • Medicine, Biology
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
  • 2017
The combination of myo-Ins plus melatonin seems to affect positively glucose metabolism, while myo -Ins only seems to improve thyroid function in women during menopausal transition.

Insomnia and menopause: a narrative review on mechanisms and treatments

Cognitive behavioral therapy represents the first-line treatment of insomnia in the general population, regardless of the presence of mood disorders and/or vasomotor symptoms (VMS), and prolonged-released melatonin should represent a first- line drug in women aged ≥ 55 years.

The value of melatonin supplementation in postmenopausal women with Helicobacter pylori-associated dyspepsia

Melatonin supplementation is useful in treating H. pylori -associated dyspepsia, particularly in postmenopausal women with lower levels of this hormone, and examine the role of Helicobacter infection.

Alternative Options to Manage Menopausal Symptoms with a Focus on Melatonin and Osteoporosis

The focus of this mini-review is to highlight the novel use of melatonin on managing menopausal symptoms and menopausal bone loss and describe food sources that are rich in melatonin.
...

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