Effects of Mechanical Insufflation‐Exsufflation on Respiratory Parameters for Patients with Chronic Airway Secretion Encumbrance.

@article{Winck2004EffectsOM,
  title={Effects of Mechanical Insufflation‐Exsufflation on Respiratory Parameters for Patients with Chronic Airway Secretion Encumbrance.},
  author={Jo{\~a}o Carlos Winck and Miguel R. Gonçalves and Cristina Bassi Lourenco and Paulo Viana and Jo{\~a}o Paulo A. Almeida and John R Bach},
  journal={Cardiopulmonary Physical Therapy},
  year={2004},
  volume={16},
  pages={25}
}
STUDY OBJECTIVES To analyze the physiologic effects and tolerance of mechanical insufflation-exsufflation (MI-E) for patients with chronic ventilatory failure of various etiologies. DESIGN Prospective clinical trial. SETTING Rehabilitation unit of a university hospital. PATIENTS OR PARTICIPANTS Thirteen patients with amyotrophic lateral sclerosis (ALS), 9 patients with severe COPD, and 7 patients with other neuromuscular disorders (oNMDs) with chronic airway secretion encumbrance and… 
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150 Citations
Background Citations
14
Methods Citations
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Results Citations
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150 Citations

Citation Type

Citation Type

Physiologic benefits of mechanical insufflation-exsufflation in children with neuromuscular diseases.
TLDR
The results confirm the good tolerance and physiologic short-term benefit of the MI-E in children with neuromuscular disease who were in a stable state.
[Indications and compliance of home mechanical insufflation-exsufflation in patients with neuromuscular diseases].
Indications and Compliance of Home Mechanical Insufflation-Exsufflation in Patients with Neuromuscular Diseases
Mechanical insufflation/exsufflation improves respiratory mechanics in critical care: Randomized crossover trial
Acute Effects of Mechanical Insufflation-Exsufflation on the Breathing Pattern in Stable Subjects With Duchenne Muscular Dystrophy
TLDR
A single treatment of MI-E in subjects with stable DMD already adapted to the device can provide beneficial changes in breathing pattern through a significant decrease in breathing frequency and rapid shallow breathing.
Effects of mechanical insufflation-exsufflation in preventing respiratory failure after extubation: a randomized controlled trial
TLDR
Inclusion of MI-E may reduce reintubation rates with consequent reduction in postextubation ICU length of stay and this technique seems to be efficient in improving the efficacy of NIV in this patient population.
Long-Term Mechanical Insufflation-Exsufflation Cough Assistance in Neuromuscular Disease: Patterns of Use and Lessons for Application
TLDR
Greater exsufflation pressures than insufflation pressures, together with a shorterinsufflation time than exsufflated time, were used and were used to promote increased cough peak flow (CPF) in conjunction with a cough.
Airway Clearance With an Optimized Mechanical Insufflation-Exsufflation Maneuver
TLDR
The optimized MI-E maneuver, applied with slow insufflation, resulted in a higher expiratory flow bias, which made the therapy more effective at moving mucus outward, compared with the standard MI- E maneuver, typically applied with fast insufflated.
Mechanical in-Exsufflation Improves the Breathing Pattern in Patients with Duchenne Muscular Dystrophy
TLDR
Changes in breathing pattern parameters resulting in an increased ribcage tidal volume, and decreased breathing rate are shown, which may help to improve lung volume recruitment and optimize gas exchanges within the alveoli.
Use of Mechanical Insufflation-Exsufflation Devices for Airway Clearance in Subjects With Neuromuscular Disease
TLDR
The current scientific evidence does not support the use of MI-E for cough augmentation in patients with neuromuscular diseases, but health-care professionals are faced with the reality of medical practice and the absence of alternatives.
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References

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TLDR
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