Effects of Lyrm1 knockdown on mitochondrial function in 3 T3-L1 murine adipocytes.

@article{Zhu2012EffectsOL,
  title={Effects of Lyrm1 knockdown on mitochondrial function in 3 T3-L1 murine adipocytes.},
  author={Guan-zhong Zhu and Min Zhang and Chun-zhao Kou and Yu-hui Ni and Chen-bo Ji and Xin-guo Cao and Xi-rong Guo},
  journal={Journal of bioenergetics and biomembranes},
  year={2012},
  volume={44 1},
  pages={225-32}
}
To explore the effects of Lyrm1 knockdown on the mitochondrial function of 3 T3-L1 adipocytes using small interfering RNA (siRNA). 3 T3-L1 preadipocytes were infected with either a negative control (NC) expression lentivirus or a Lyrm1-shRNA expression lentivirus and induced to differentiate. The knockdown efficiency of Lrym1-specific shRNA in 3 T3-L1 cells was evaluated by real-time PCR. The ultrastructure of the mitochondria in adipocytes was visualized using transmission electron microscopy… CONTINUE READING