Effects of Low-Level Laser Therapy on M1-Related Cytokine Expression in Monocytes via Histone Modification

@inproceedings{Chen2014EffectsOL,
  title={Effects of Low-Level Laser Therapy on M1-Related Cytokine Expression in Monocytes via Histone Modification},
  author={Chia-Hsin Owen Chen and Chau-Zen Wang and Yan-Hsiung Wang and Wei-Ting Liao and Yi-Jen Chen and Chang-Hung Kuo and Hsuan-Fu Kuo and Chih-Hsing Hung},
  booktitle={Mediators of inflammation},
  year={2014}
}
Low-level laser therapy (LLLT) has been used in the treatment of radiotherapy-induced oral mucositis and allergic rhinitis. However, the effects of LLLT on human monocyte polarization into M1 macrophages are unknown. To evaluate the effects of LLLT on M1-related cytokine and chemokine production and elucidate the mechanism, the human monocyte cell line THP-1 was treated with different doses of LLLT. The expression of M1-related cytokines and chemokines (CCL2, CXCL10, and TNF-α) was determined… CONTINUE READING

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