Effects of Low Concentrations of Nitrous Oxide on Rat Fetuses

@article{Vieira1980EffectsOL,
  title={Effects of Low Concentrations of Nitrous Oxide on Rat Fetuses},
  author={E. Vieira and Cleaton-Jones and J. Austin and D. Moyes and R. Shawl},
  journal={Anesthesia \& Analgesia},
  year={1980},
  volume={59},
  pages={175–177}
}
The long-term inhalation of air polluted with nitrous oxide has been implicated in spontaneous abortions and fetal abnormalities in operating room personnel. Studies with 1% and 0.5% N2O in air have confirmed the adverse effects of dilute concentrations of N2O in pregnant rats. The present study was designed to determine the threshold concentration of nitrous oxide necessary to produce adverse responses in pregnant rats. Wistar albino rats were mated in an environmental chamber and conception… Expand
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