Effects of Lindane on Steroidogenesis and Steroidogenic Acute Regulatory Protein Expression1

@inproceedings{Walsh2000EffectsOL,
  title={Effects of Lindane on Steroidogenesis and Steroidogenic Acute Regulatory Protein Expression1},
  author={Lance P. Walsh and Douglas M. Stocco},
  booktitle={Biology of reproduction},
  year={2000}
}
  • Lance P. Walsh, Douglas M. Stocco
  • Published in Biology of reproduction 2000
  • Biology, Medicine
  • Abstract Lindane, the γ isomer of hexachlorocyclohexane (HCH), is one of the oldest synthetic pesticides still in use worldwide. Numerous reports have shown that this pesticide adversely affects reproductive function in animals. Although the pathogenesis of reproductive dysfunction is not yet fully understood, recent reports indicate that lindane can directly inhibit adrenal and gonadal steroidogenesis. Because Leydig cells play a pivotal role in male reproductive function through the… CONTINUE READING

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